Pain

Updated January 12, 2025. First time visitor? Start here.

🟢 Dechra Redonyl Ultra Feline

Dechra Redonyl Ultra Feline

The acronym “PEA” used here refers to palmitoylethanolamide, and should not be confused with phenylethylamine.

Arthritis

Pain

Palmitoylethanolamide (PEA)

manufacturer page 

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😺 Luna Says

Dad thinks this helps me with arthritis and other pain. He was unable to find another source which is “ultra-micronized,” which allegedly helps with something called “bioavailability.” Silly humans and their fancy words! Just mix this in my food already.

References and resources
  1. Cifelli P, Ruffolo G, Ceccanti M, Cambieri C, Libonati L, Palma E, Inghilleri M. Classical and Unexpected Effects of Ultra-Micronized PEA in Neuromuscular Function. Biomolecules. 2022; 12(6):758. doi:10.3390/biom12060758 
  2. Rusbridge C. Neuropathic pain in cats: mechanisms and multimodal management. Journal of Feline Medicine and Surgery. 2024;26(5). doi:10.1177/1098612X241246518 
  3. “Due to the patents held on Redonyl Ultra, no other animal health nutraceutical can contain micronized or ultramicronized PEA.” — Dechra unveils skin-supporting Redonyl Ultra Feline (2022) https://todaysveterinarybusiness.com/redonyl-ultra-feline-dechra/  (retrieved 2024-10-20)

🟢 Generic Gabapentin Compounded Tablet

Generic Gabapentin Compounded Tablet

Anxiety

Drugs

Pain

View on Chewy 

References and resources
  1. Adrian D, Papich MG, Baynes R, Stafford E, Lascelles BDX. The pharmacokinetics of gabapentin in cats. J Vet Intern Med. 2018; 32: 1996-2002. doi:10.1111/jvim.15313 
  2. Buckley C, Griffin C, Anderson H, Moore SA. Presumed gabapentin-induced myoclonus in two cats. JFMS Open Rep. 2024 Nov 28;10(2):20551169241273634. doi:10.1177/20551169241273634 
  3. Di Cesare F, Negro V, Ravasio G, Villa R, Draghi S, Cagnardi P. Gabapentin: Clinical Use and Pharmacokinetics in Dogs, Cats, and Horses. Animals. 2023; 13(12):2045. doi:10.3390/ani13122045 
  4. Fantinati M, Trnka J, Signor A, et al. Appetite-stimulating effect of gabapentin vs mirtazapine in healthy cats post-ovariectomy. Journal of Feline Medicine and Surgery. 2020;22(12):1176-1183. doi:10.1177/1098612X20916391 
  5. Guedes AGP, Meadows JM, Pypendop BH, Johnson EG, Zaffarano B. Assessment of the effects of gabapentin on activity levels and owner-perceived mobility impairment and quality of life in osteoarthritic geriatric cats. J Am Vet Med Assoc. 2018 Sep 1;253(5):579-585. doi:10.2460/javma.253.5.579 
  6. Madan RD, Cenani A, Montgomery E, Azevedo T, Vernau KM, Brosnan RJ. Pregabalin produces similar effects as gabapentin for preanesthetic sedation in cats. J Am Vet Med Assoc. 2023 Dec 22;262(3):359-363. doi:10.2460/javma.23.09.0493 
  7. Quimby JM, Lorbach SK, Saffire A, et al. Serum concentrations of gabapentin in cats with chronic kidney disease. Journal of Feline Medicine and Surgery. 2022;24(12):1260-1266. doi:10.1177/1098612X221077017 
  8. Quimby JM, Jones SE, Saffire A, et al. Assessment of the effect of gabapentin on blood pressure in cats with and without chronic kidney disease. Journal of Feline Medicine and Surgery. 2024;26(5). doi:10.1177/1098612X241240326 
  9. Rusbridge C. Neuropathic pain in cats: mechanisms and multimodal management. Journal of Feline Medicine and Surgery. 2024;26(5). doi:10.1177/1098612X241246518 
  10. Siao KT, Pypendop BH, Ilkiw JE. Pharmacokinetics of gabapentin in cats. Am J Vet Res. 2010 Jul;71(7):817-21. doi:10.2460/ajvr.71.7.817 
  11. Vanderhoof C. Gabapentin for Cats: A Common Option for Pain and Anxiety. GoodRx. 2024. https://www.goodrx.com/pet-health/cat/gabapentin-for-cats 
  12. Zand L, McKian KP, Qian Q. Gabapentin toxicity in patients with chronic kidney disease: a preventable cause of morbidity. Am J Med. 2010 Apr;123(4):367-73. doi:10.1016/j.amjmed.2009.09.030 
  13. Zour E, Lodhi SA, Nesbitt RU, Silbering SB, Chaturvedi PR. Stability studies of gabapentin in aqueous solutions. Pharm Res. 1992 May;9(5):595-600. doi:10.1023/a:1015833622943 

Pain references and resources

  1. Chronic Pain Educational Toolkit. American Association of Feline Practitioners. 2024. https://catvets.com/chronic-pain-toolkit 
  2. Delsart A, Castel A, Dumas G, Otis C, Lachance M, Barbeau-Grégoire M, Lussier B, Péron F, Hébert M, Lapointe N, Moreau M, Martel-Pelletier J, Pelletier JP, Troncy E. Non-invasive electroencephalography in awake cats: Feasibility and application to sensory processing in chronic pain. J Neurosci Methods. 2024 Nov;411:110254. doi:10.1016/j.jneumeth.2024.110254 
  3. Jordan DG, Ray JD. Management of Chronic Pain in Cats. Today’s Veterinary Practice. 2012. https://todaysveterinarypractice.com/pain_management/focus-on-pharmacology-management-of-chronic-pain-in-cats/ 
  4. KuKanich B. Outpatient oral analgesics in dogs and cats beyond nonsteroidal antiinflammatory drugs: an evidence-based approach. Vet Clin North Am Small Anim Pract. 2013 Sep;43(5):1109-25. doi:10.1016/j.cvsm.2013.04.007 
  5. Monteiro BP, Steagall PV. Chronic pain in cats: Recent advances in clinical assessment. Journal of Feline Medicine and Surgery. 2019;21(7):601-614. doi:10.1177/1098612X19856179 
  6. Monteiro, B.P., Lascelles, B.D.X., Murrell, J., Robertson, S., Steagall, P.V.M. and Wright, B. (2023), 2022 WSAVA guidelines for the recognition, assessment and treatment of pain. J Small Anim Pract, 64: 177-254. doi:10.1111/jsap.13566 
  7. Quimby JM. Maropitant Use in Cats. Today’s Veterinary Practice. 2020. https://todaysveterinarypractice.com/pharmacology/maropitant-use-in-cats/ 
  8. Rusbridge C. Neuropathic pain in cats: mechanisms and multimodal management. Journal of Feline Medicine and Surgery. 2024;26(5). doi:10.1177/1098612X241246518 
  9. Vanderhoof C. Gabapentin for Cats: A Common Option for Pain and Anxiety. GoodRx. 2024. https://www.goodrx.com/pet-health/cat/gabapentin-for-cats 

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