Anxiety
Updated March 28, 2025.
🟢 Feliway Classic Calming Diffuser Refill
1 ct
3 ct
6 ct
🟢 Feliway Classic Calming Diffuser Starter Kit
References and resources
- Gunn-Moore DA, Cameron ME. A pilot study using synthetic feline facial pheromone for the management of feline idiopathic cystitis. Journal of Feline Medicine and Surgery. 2004;6(3):133-138. doi:10.1016/j.jfms.2004.01.006
🟢 Feliway Classic Calming Spray (60 mL)
🟢 Feliway Optimum Enhanced Calming Pheromone Diffuser Refill
1 ct
View on Amazon 💲 | Chewy | Feliway
3 ct
View on Amazon 💲 | Amazon 💲 | Chewy | Feliway
6 ct
View on Amazon 💲 | Chewy | Feliway
😺 Luna Says
We’ve found that this works better than the Feliway “Classic” variety for managing my cystitis.
🟢 Feliway Optimum Enhanced Calming Pheromone Diffuser Starter Kit
View on Amazon 💲 | Chewy | Feliway
😺 Luna Says
We’ve found that this works better than the Feliway “Classic” variety for managing my cystitis.
🟢 Frisco Senior Litter Box
View on Chewy
😺 Luna Says
The low sides make getting in and out easy on my arthritic joints. Having pain-free access nearby helps with my cystitis. The large area means less difficulty and anxiety finding the perfect spot for a deposit. And Dad says it works great with the Petivity litter box monitor.
🟢 Generic Gabapentin Compounded Tablet
View on Chewy
References and resources
- Adrian D, Papich MG, Baynes R, Stafford E, Lascelles BDX. The pharmacokinetics of gabapentin in cats. J Vet Intern Med. 2018; 32: 1996-2002. doi:10.1111/jvim.15313
- Buckley C, Griffin C, Anderson H, Moore SA. Presumed gabapentin-induced myoclonus in two cats. JFMS Open Rep. 2024 Nov 28;10(2):20551169241273634. doi:10.1177/20551169241273634
- Di Cesare F, Negro V, Ravasio G, Villa R, Draghi S, Cagnardi P. Gabapentin: Clinical Use and Pharmacokinetics in Dogs, Cats, and Horses. Animals. 2023; 13(12):2045. doi:10.3390/ani13122045
- Fantinati M, Trnka J, Signor A, et al. Appetite-stimulating effect of gabapentin vs mirtazapine in healthy cats post-ovariectomy. Journal of Feline Medicine and Surgery. 2020;22(12):1176-1183. doi:10.1177/1098612X20916391
- Guedes AGP, Meadows JM, Pypendop BH, Johnson EG, Zaffarano B. Assessment of the effects of gabapentin on activity levels and owner-perceived mobility impairment and quality of life in osteoarthritic geriatric cats. J Am Vet Med Assoc. 2018 Sep 1;253(5):579-585. doi:10.2460/javma.253.5.579
- Kaufman KR, Parikh A, Chan L, Bridgeman M, Shah M. Myoclonus in renal failure: Two cases of gabapentin toxicity. Epilepsy Behav Case Rep. 2013 Dec 29;2:8-10. doi:10.1016/j.ebcr.2013.12.002
- Madan RD, Cenani A, Montgomery E, Azevedo T, Vernau KM, Brosnan RJ. Pregabalin produces similar effects as gabapentin for preanesthetic sedation in cats. J Am Vet Med Assoc. 2023 Dec 22;262(3):359-363. doi:10.2460/javma.23.09.0493
- Miller A, Price G. Gabapentin toxicity in renal failure: the importance of dose adjustment. Pain Med. 2009 Jan;10(1):190-2. doi:10.1111/j.1526-4637.2008.00492.x
- Quimby JM, Lorbach SK, Saffire A, et al. Serum concentrations of gabapentin in cats with chronic kidney disease. Journal of Feline Medicine and Surgery. 2022;24(12):1260-1266. doi:10.1177/1098612X221077017
- Quimby JM, Jones SE, Saffire A, et al. Assessment of the effect of gabapentin on blood pressure in cats with and without chronic kidney disease. Journal of Feline Medicine and Surgery. 2024;26(5). doi:10.1177/1098612X241240326
- Rusbridge C. Neuropathic pain in cats: mechanisms and multimodal management. Journal of Feline Medicine and Surgery. 2024;26(5). doi:10.1177/1098612X241246518
- Siao KT, Pypendop BH, Ilkiw JE. Pharmacokinetics of gabapentin in cats. Am J Vet Res. 2010 Jul;71(7):817-21. doi:10.2460/ajvr.71.7.817
- Vanderhoof C. Gabapentin for Cats: A Common Option for Pain and Anxiety. GoodRx. 2024. https://www.goodrx.com/pet-health/cat/gabapentin-for-cats
- Zand L, McKian KP, Qian Q. Gabapentin toxicity in patients with chronic kidney disease: a preventable cause of morbidity. Am J Med. 2010 Apr;123(4):367-73. doi:10.1016/j.amjmed.2009.09.030
- Zour E, Lodhi SA, Nesbitt RU, Silbering SB, Chaturvedi PR. Stability studies of gabapentin in aqueous solutions. Pharm Res. 1992 May;9(5):595-600. doi:10.1023/a:1015833622943
🟢 Purina Calming Care (30 ct)
References and resources
- Davis H, Franco P, Gagne J, McGowan RTS, Hawley J, Lappin M. Effect of Bifidobacterium longum 999 supplementation on stress associated findings in cats with FHV-1 infection. In: 2021 ACVIM Forum Research Abstract Program. J Vet Intern Med. 2021 Nov;35(6):2943-3204. doi:10.1111/jvim.16220
- Lilly ML. Nutritional Intervention for Feline Stress. Today’s Veterinary Practice. 2022. https://todaysveterinarypractice.com/nutrition/feline-stress-nutrition/
- McGowan RTS, Barnett HR, Czarnecki-Maulden G, et al. Tapping into the “gut feelings”: impact of BL999 (Bifidobacterium longum) on anxiety in dogs. Nestlé Purina Research. 2018. https://fearfreepets.com/wp-content/uploads/delightful-downloads/2018/11/Ragen-McGowan-2018-VBS-Abstract.pdf
🟢 Vetoquinol Zylkene Calming Supplement (75 mg)
14 ct
30 ct
60 ct
View on Chewy
120 ct
References and resources
- Beata C, Beaumont-Graff E, Coll V, Cordel J, Marion M, Massal N, Marlois N, Tauzin J. Effect of alpha-casozepine (Zylkene) on anxiety in cats. Journal of Veterinary Behavior. 2007;2(2):40-46. doi:10.1016/j.jveb.2007.02.002
- Landsberg G, Milgram B, Mougeot I, Kelly S, de Rivera C. Therapeutic effects of an alpha-casozepine and L-tryptophan supplemented diet on fear and anxiety in the cat. J Feline Med Surg. 2017 Jun;19(6):594-602. doi:10.1177/1098612X16669399
🟢 VRS flo cat (powder, 90 g)
Promote optimal urinary tract health and function.
View on VRS Health
😺 Luna Says
Please be aware this product contains a small amount of cranberry.
🟢 Zoetis Bonqat
References and resources
- Lamminen T, Doedée A, Hyttilä-Hopponen M, Kaskinoro J. Pharmacokinetics of single and repeated oral doses of pregabalin oral solution formulation in cats. J Vet Pharmacol Ther. 2022 Jul;45(4):385-391. doi:10.1111/jvp.13061
- Mayoral V, Galvez R, Ferrándiz M, Miguéns Vázquez X, Cordero-García C, Alcántara Montero A, Pérez C, Pérez-Páramo M. Pregabalin vs. gabapentin in the treatment of neuropathic pain: a comprehensive systematic review and meta-analysis of effectiveness and safety. Front Pain Res (Lausanne). 2025 Jan 7;5:1513597. doi:10.3389/fpain.2024.1513597
- Rusbridge C. Pregabalin - 5 things you should know about prescribing in dogs and cats. 2023. https://youtu.be/fr3gu6S6guE
Anxiety references and resources
- Davis H, Franco P, Gagne J, McGowan RTS, Hawley J, Lappin M. Effect of Bifidobacterium longum 999 supplementation on stress associated findings in cats with FHV-1 infection. In: 2021 ACVIM Forum Research Abstract Program. J Vet Intern Med. 2021 Nov;35(6):2943-3204. doi:10.1111/jvim.16220
- Beata C, Beaumont-Graff E, Coll V, Cordel J, Marion M, Massal N, Marlois N, Tauzin J. Effect of alpha-casozepine (Zylkene) on anxiety in cats. Journal of Veterinary Behavior. 2007;2(2):40-46. doi:10.1016/j.jveb.2007.02.002
- Hampton A, Ford A, Cox RE 3rd, Liu CC, Koh R. Effects of music on behavior and physiological stress response of domestic cats in a veterinary clinic. J Feline Med Surg. 2020 Feb;22(2):122-128. doi:10.1177/1098612X19828131
- Lilly ML. Nutritional Intervention for Feline Stress. Today’s Veterinary Practice. 2022. https://todaysveterinarypractice.com/nutrition/feline-stress-nutrition/
- McGowan RTS, Barnett HR, Czarnecki-Maulden G, et al. Tapping into the “gut feelings”: impact of BL999 (Bifidobacterium longum) on anxiety in dogs. Nestlé Purina Research. 2018. https://fearfreepets.com/wp-content/uploads/delightful-downloads/2018/11/Ragen-McGowan-2018-VBS-Abstract.pdf
- Vanderhoof C. Gabapentin for Cats: A Common Option for Pain and Anxiety. GoodRx. 2024. https://www.goodrx.com/pet-health/cat/gabapentin-for-cats
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