βOne cat was prescribed budesonide administered PO due to the presence of complete heart block with 4-chamber dilation and concerns for provoking heart failure; the clinician cited anecdotal evidence that budesonide might cause less plasma volume expansion than prednisolone. After steroid administration, NT-proBNP in this cat increased by 93% (707-1367 pmol/L). Four months after the study ended and while still receiving budesonide, the cat developed a large volume of abdominal effusion. The cause of effusion was not determined. At the time of writing, no other cats had developed signs consistent with CHF.β β Block CL, Oyama MA. Echocardiographic and biomarker evidence of plasma volume expansion after short-term steroids administered orally in cats. J Vet Intern Med. 2020 Jan;34(1):29-34. doi:10.1111/jvim.15678Β (retrieved 2025-01-10)
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